The Apollo/Saturn V Center was built to house a restored Saturn V launch vehicle (which is suspended from the ceiling) and features other exhibits related to the Apollo program. Until the structure was built, the Saturn V you see here was displayed horizontally for many years outdoors just south of the Vehicle Assembly Building and left to the elements. The rocket's first stage is S-IC-T (a test stage) and the second (S-II) and third stages (S-IVB) are from SA-514, which would have been used for the canceled Apollo 19 mission. The interstages between the first and second stages and between the second and third stages are not present, but the Instrument Unit is on display (showing the internal equipment). The booster has been repainted to resemble Apollo 11's Saturn V, and its command module is the boilerplate BP-30.

Other large exhibits include an unused Apollo command/service module (CSM-119) and an unused Lunar Module (LM-9). CSM-119 was designated for a possible Skylab rescue mission and as a backup for the Apollo–Soyuz Test Project. LM-9 was originally scheduled to be used on Apollo 15, but when missions after Apollo 17 were canceled, a later LM (LM-10) was used instead. You'll also find a Lunar Module simulator, a replica of a lunar rover, an Apollo-era space suit and Gene Cernan's Apollo 17 suit, Alan Shepard's Corvette, a piece of Apollo 13's Lunar Module returned by the astronauts, a tool cart like the one used on the Moon by Apollo 14, and a van used to carry astronauts to the launch pad.